ISP · Northeast
Nonstop into Islip, NY
18 U.S. airports fly here without a layover, grouped by how long you'd be in the air.
18 of 18 nonstop routes
Leave after work
Under 2 hours9 citysBaltimore, MD
BWI · Baltimore/Washington International Thurgood Marshall Airport
45m
About 3 flights a day
Southwest
Boston, MA
BOS · Boston Logan International Airport
51m
About 3 flights a day
Cape Air
Myrtle Beach, SC
MYR · Myrtle Beach International Airport
1h 23m
4 flights a week
Frontier, Breeze
SeasonalNonstops out of MYR →Concord, NC
USA · Concord-Padgett Regional Airport
1h 24m
3 flights a week
Raleigh/Durham, NC
RDU · Raleigh-Durham International Airport
1h 11m
3 flights a week
Breeze
Charleston, SC
CHS · Charleston International Airport
1h 32m
3 flights a week
Wilmington, NC
ILM · Wilmington International Airport
1h 15m
3 flights a week
Breeze, Avelo
Norfolk, VA
ORF · Norfolk International Airport
54m
2 flights a week
Breeze
Richmond, VA
RIC · Richmond International Airport
54m
A couple of flights a week
Breeze
Easy weekend
2 to 3 hours9 citysOrlando, FL
MCO · Orlando International Airport
2h 9m
About 4 flights a day
Southwest, JetBlue, Frontier
West Palm Beach, FL
PBI · Palm Beach International Airport
2h 19m
About 3 flights a day
Southwest, JetBlue, Frontier
Tampa, FL
TPA · Tampa International Airport
2h 17m
About one a day
Frontier, Southwest, JetBlue
Fort Lauderdale, FL
FLL · Fort Lauderdale Hollywood International Airport
2h 25m
About one a day
JetBlue, Frontier
Fort Myers, FL
RSW · Southwest Florida International Airport
2h 29m
6 flights a week
Breeze, JetBlue
Miami, FL
MIA · Miami International Airport
2h 31m
5 flights a week
Southwest
SeasonalNonstops out of MIA →Vero Beach, FL
VRB · Vero Beach Regional Airport
2h 16m
3 flights a week
Breeze
Lakeland, FL
LAL · Lakeland Linder International Airport
2h 19m
A couple of flights a week
Avelo
SeasonalNonstops out of LAL →Sarasota, FL
SRQ · Sarasota Bradenton International Airport
2h 25m
A couple of flights a week
Long weekend
3 to 5 hours0 citysNo nonstops in the three to five hour range from this airport.
Worth the extra days
5 hours and up0 citysNothing over five hours nonstop from here, which is normal for most Midwest airports. Hawaii and Alaska usually mean one connection.
Flip it: where can you fly nonstop from ISP? →
Nonstop route data from the U.S. Department of Transportation (BTS T-100), covering 2025-06..2026-05, last updated 2026-09-02. Domestic routes only. Airlines change schedules, so an advisor confirms before you book.
Want to know if service changes?
Airlines add and cut routes every season. Leave your email and we'll tell you when nonstop service into ISP changes.
Somewhere else in mind?
Getting there is the easy part.
Tell us your dates and your pace. An advisor comes back with real options, flights included.
Start planning →