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MDE · South America

Nonstop into Medellín, CO

5 U.S. airports fly here without a layover, grouped by how long you'd be in the air.

Nonstop service reported by U.S. carriers only; a foreign airline may fly routes not shown here.

5 of 5 nonstop routes

Leave after work

Under 2 hours0 citys

No nonstops under two hours from here. Common for smaller airports.

Easy weekend

2 to 3 hours2 citys

  • Miami, FL

    MIA · Miami International Airport

    2h 55m

    About 2 flights a day

    American

    Nonstops out of MIA →
  • San Juan, PR

    San Juan, PR

    SJU · Luis Munoz Marin International Airport

    2h 28m

    About one a day

    JetBlue

    Photo: Nils Huenerfuerst / Unsplash

    Nonstops out of SJU →

Long weekend

3 to 5 hours3 citys

Worth the extra days

5 hours and up0 citys

Nothing over five hours nonstop from here, which is normal for most Midwest airports. Hawaii and Alaska usually mean one connection.

Nonstop route data from the U.S. Department of Transportation (BTS T-100 International), covering 2025-06..2026-05, last updated 2026-09-02. International routes are reported by U.S. carriers only. Airlines change schedules, so an advisor confirms before you book.

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