STL · Midwest
Nonstop into St Louis, MO
65 U.S. airports fly here without a layover, grouped by how long you'd be in the air.
65 of 65 nonstop routes
Leave after work
Under 2 hours37 citysChicago, IL
ORD · Chicago O'Hare International Airport
47m
Many flights a day
Atlanta, GA
ATL · Hartsfield Jackson Atlanta International Airport
1h 16m
Many flights a day
Delta, Southwest, Frontier
Denver, CO
DEN · Denver International Airport
1h 35m
Many flights a day
Washington, DC
DCA · Ronald Reagan Washington National Airport
1h 52m
Many flights a day
Dallas-Fort Worth, TX
DFW · Dallas Fort Worth International Airport
1h 18m
Many flights a day
Minneapolis, MN
MSP · Minneapolis–Saint Paul International Airport / Wold–Chamberlain Field
1h 5m
Many flights a day
Detroit, MI
DTW · Detroit Metropolitan Wayne County Airport
1h 12m
About 5 flights a day
Dallas, TX
DAL · Dallas Love Field
1h 18m
About 5 flights a day
Southwest
Charlotte, NC
CLT · Charlotte Douglas International Airport
1h 30m
About 5 flights a day
American, Southwest
Chicago, IL
MDW · Chicago Midway International Airport
45m
About 5 flights a day
Southwest
Houston, TX
HOU · William P. Hobby Airport
1h 36m
About 4 flights a day
Southwest
Nashville, TN
BNA · Nashville International Airport
49m
About 4 flights a day
Baltimore, MD
BWI · Baltimore/Washington International Thurgood Marshall Airport
1h 51m
About 3 flights a day
Southwest
Houston, TX
IAH · George Bush Intercontinental Airport
1h 37m
About 3 flights a day
Kansas City, MO
MCI · Kansas City International Airport
39m
About 3 flights a day
Southwest
Austin, TX
AUS · Austin Bergstrom International Airport
1h 40m
About 3 flights a day
Southwest
Omaha, NE
OMA · Eppley Airfield
51m
About 2 flights a day
Southwest
New Orleans, LA
MSY · Louis Armstrong New Orleans International Airport
1h 27m
About 2 flights a day
Dulles, VA
IAD · Washington Dulles International Airport
1h 47m
About one a day
Regional partners: GoJet
Cleveland, OH
CLE · Cleveland Hopkins International Airport
1h 15m
About one a day
Southwest
Milwaukee, WI
MKE · General Mitchell International Airport
54m
About one a day
Southwest
Columbus, OH
CMH · John Glenn Columbus International Airport
1h 6m
About one a day
Southwest
Raleigh/Durham, NC
RDU · Raleigh-Durham International Airport
1h 47m
About one a day
Southwest
Des Moines, IA
DSM · Des Moines International Airport
42m
About one a day
Southwest
Wichita, KS
ICT · Wichita Dwight D. Eisenhower National Airport
56m
About one a day
Southwest
Oklahoma City, OK
OKC · OKC Will Rogers World Airport
1h 5m
About one a day
Southwest
Jacksonville, FL
JAX · Jacksonville International Airport
1h 48m
About one a day
Southwest
San Antonio, TX
SAT · San Antonio International Airport
1h 46m
About one a day
Southwest
Little Rock, AR
LIT · Bill & Hillary Clinton National Airport/Adams Field
52m
About one a day
Southwest
Tulsa, OK
TUL · Tulsa International Airport
52m
About one a day
Southwest
Pittsburgh, PA
PIT · Pittsburgh International Airport
1h 24m
About one a day
Southwest
Panama City Beach, FL
ECP · Northwest Florida Beaches International Airport
1h 30m
About one a day
Southwest
Pensacola, FL
PNS · Pensacola International Airport
1h 27m
5 flights a week
Southwest
Charleston, SC
CHS · Charleston International Airport
1h 43m
5 flights a week
Valparaiso, FL
VPS · Destin-Fort Walton Beach Airport
1h 28m
4 flights a week
Southwest
Savannah, GA
SAV · Savannah Hilton Head International Airport
1h 41m
3 flights a week
Myrtle Beach, SC
MYR · Myrtle Beach International Airport
1h 45m
A couple of flights a week
Southwest
Easy weekend
2 to 3 hours16 citysNew York, NY
LGA · LaGuardia Airport
2h 13m
Many flights a day
Orlando, FL
MCO · Orlando International Airport
2h 7m
Many flights a day
Southwest, Frontier
Phoenix, AZ
PHX · Phoenix Sky Harbor International Airport
2h 30m
Many flights a day
Las Vegas, NV
LAS · Harry Reid International Airport
2h 41m
About 6 flights a day
Southwest, Frontier
Boston, MA
BOS · Boston Logan International Airport
2h 36m
About 4 flights a day
Philadelphia, PA
PHL · Philadelphia International Airport
2h
About 4 flights a day
Tampa, FL
TPA · Tampa International Airport
2h 2m
About 3 flights a day
Southwest
Miami, FL
MIA · Miami International Airport
2h 28m
About 3 flights a day
American, Southwest
Fort Myers, FL
RSW · Southwest Florida International Airport
2h 17m
About 3 flights a day
Southwest
Newark, NJ
EWR · Newark Liberty International Airport
2h 11m
About 3 flights a day
Salt Lake City, UT
SLC · Salt Lake City International Airport
2h 19m
About 3 flights a day
Cancún, MX
CUN · Cancún International Airport
2h 45m
About 2 flights a day
Southwest, Frontier
Fort Lauderdale, FL
FLL · Fort Lauderdale Hollywood International Airport
2h 27m
About 2 flights a day
Southwest, Spirit
Sarasota, FL
SRQ · Sarasota Bradenton International Airport
2h 9m
About one a day
New York, NY
JFK · John F. Kennedy International Airport
2h 15m
4 flights a week
Delta
SeasonalNonstops out of JFK →West Palm Beach, FL
PBI · Palm Beach International Airport
2h 25m
3 flights a week
Southwest
SeasonalNonstops out of PBI →
Long weekend
3 to 5 hours12 citysLos Angeles, CA
LAX · Los Angeles International Airport
3h 9m
About 3 flights a day
Seattle, WA
SEA · Seattle–Tacoma International Airport
3h 20m
About 2 flights a day
Alaska, Southwest
San Francisco, CA
SFO · San Francisco International Airport
3h 22m
About 2 flights a day
San Diego, CA
SAN · San Diego International Airport
3h 3m
About one a day
Southwest
Sacramento, CA
SMF · Sacramento International Airport
3h 13m
6 flights a week
Southwest
Burbank, CA
BUR · Hollywood Burbank/Bob Hope Airport
3h 6m
5 flights a week
Southwest
Long Beach, CA
LGB · Long Beach International Airport
3h 8m
5 flights a week
Southwest
SeasonalNonstops out of LGB →Punta Cana, DO
PUJ · Punta Cana International Airport
4h 19m
4 flights a week
Portland, OR
PDX · Portland International Airport
3h 24m
2 flights a week
Southwest, Alaska
SeasonalNonstops out of PDX →Montego Bay, JM
MBJ · Sangster International Airport
3h 22m
A couple of flights a week
Southwest
SeasonalNonstops out of MBJ →Puerto Vallarta, MX
PVR · Puerto Vallarta International Airport
3h 6m
A couple of flights a week
Alaska, Southwest
SeasonalNonstops out of PVR →San José del Cabo, MX
SJD · Los Cabos International Airport
3h 12m
A couple of flights a week
Southwest, American
Worth the extra days
5 hours and up0 citysNothing over five hours nonstop from here, which is normal for most Midwest airports. Hawaii and Alaska usually mean one connection.
Flip it: where can you fly nonstop from STL? →
Nonstop route data from the U.S. Department of Transportation (BTS T-100), covering 2025-06..2026-05, last updated 2026-09-02. Domestic routes only. Airlines change schedules, so an advisor confirms before you book.
Want to know if service changes?
Airlines add and cut routes every season. Leave your email and we'll tell you when nonstop service into STL changes.
Somewhere else in mind?
Getting there is the easy part.
Tell us your dates and your pace. An advisor comes back with real options, flights included.
Start planning →