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STL · Midwest

Nonstop from St Louis, MO

65 cities you can reach without a layover, 60 in the U.S. and 5 abroad, grouped by how long you'd be in the air.

65 of 65 nonstop routes

Leave after work

Under 2 hours43 destinations

Easy weekend

2 to 3 hours9 destinations

Long weekend

3 to 5 hours13 destinations

Worth the extra days

5 hours and up0 destinations

Nothing over five hours nonstop from here, which is normal for most Midwest airports. Hawaii and Alaska usually mean one connection.

Nothing over five hours flies nonstop from STL. That's normal for a lot of the country. Hawaii, Alaska, and Europe typically mean one connection, and an advisor picks the one least likely to cost you a day.

Nonstop service reported by U.S. carriers only; a foreign airline may fly routes not shown here.

Flip it: who flies nonstop into STL →

Nonstop route data from the U.S. Department of Transportation (BTS T-100), covering 2025-06..2026-05, last updated 2026-09-02. Includes domestic routes and international routes reported by U.S. carriers. Airlines change schedules, so an advisor confirms before you book.

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